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Grant awarded to Zoology Faculty for work on Alzheimer’s research and Circadian clocks

Posted by The College of Science at OSU on September 3, 2009

The committee for the Oregon Partnership for Alzheimer’s Research announces the recipients of the 2009 – 2010 OPAR grants.

Congratulations OPAR Grant Recipients!

The Oregon Partnership for Alzheimer’s Research Committee is pleased to announce the recipients of the 2009- 2010 OPAR grants. These grants are made possible through the Oregon Tax Checkoff program.  You can support this program when you file your state income tax.  Support researchers who are entering the field of Alzheimer’s disease research or who are pursuing new directions in Alzheimer’s research.

Jadwiga M. Giebultowicz, Ph.D. – “The Role of the Circadian Clock in Alzheimer’s Disease”
Humans and other animals have an internal clock system that regulates sleep-wake patterns.  This internal system is called a circadian clock.  Circadian clocks synchronize biological processes within an organism and coordinate them with the solar day/night cycle. Deregulation of circadian synchronization leads to sleep disturbances and age-related diseases. Recent data suggest that disruption of the circadian system and age-related pathologies are not understood. We recently showed that disruption of the circadian clock leads to increased levels of oxidative damage in the model organism, Drosophila melanogaster. Since impaired circadian rhythms and oxidative stress are linked to Alzheimer’s disease (AD), we initiated a novel study aimed to decipher how the circadian clock protects against age-related oxidative damage.


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